Neuroscience

many of the quant-ities related to suffering are based on perceptions and similar uncertain infer-ences. The uncertainty will necessarily increase frustration since it means the predictions of reward often go wrong . More fundamentally, the computed reward loss can be uncertain, even illusory .

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Their finding is part of wider realization in the neuroscience community, that our brain does not simply react to what comes in through our senses. Instead, we have a predictive brain, that permanently predicts what comes next. The expected sensory input is then suppressed. We see the world from the inside out, rather than from the outside in.

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