many of the quant-ities related to suffering are based on perceptions and similar uncertain infer-ences. The uncertainty will necessarily increase frustration since it means the predictions of reward often go wrong . More fundamentally, the computed reward loss can be uncertain, even illusory .
We build upon the key fact that the brain is (part of) the body and as such, like any other bodily organ, the brain is made of cells. The focus on cellular rather than neural, brain processing allows us to underscore the idea that flexible responses to changes in the environments requires flexible adjustments not only through neural, but also... See more