Neuroscience

These fndings indicate that, while MBCT is a reliable and e

fcacious intervention,

there is a need to address the sustainability of treatment-related improvements in patients with

BD

many of the quant-ities related to suffering are based on perceptions and similar uncertain infer-ences. The uncertainty will necessarily increase frustration since it means the predictions of reward often go wrong . More fundamentally, the computed reward loss can be uncertain, even illusory .