Sublime

The single most powerful item in our preventive tool kit is exercise, which has a two-pronged impact on Alzheimer’s disease risk: it helps maintain glucose homeostasis, and it improves the health of our vasculature.

These approaches overlap, as we’ll see: reducing cardiovascular risk by targeting specific lipoproteins (cholesterol) may also reduce Alzheimer’s disease risk, for example, though not cancer. The steps we take to improve metabolic health and prevent type 2 diabetes almost certainly reduce the risk of cardiovascular disease, cancer, and Alzheimer’s

This is because deep abdominal fat, the kind that wraps itself around your heart, liver, and other major organs, not only receives more blood but has four times more cortisol receptors than subcutaneous fat (the fat that you can “pinch” below the skin).

“Moderation” is a cop-out answer—a deliberate attempt to evade the hard work of searching for dietary truths.