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Diseases have global networks of stakeholders: Imagine a new insulin treatment funded, governed, and owned by diabetics. Our marketplace connects researchers with patients to enable this.

My dear friend Jordan Richman reminded me last year—”It doesn’t matter how many followers you have. It matters who follows you.” This is certainly a truism to live by. It’s something young people seem to be realizing more and more by the day. Being back in New York, I’ve noticed young people seem disinterested in follower counts—perhaps to the poin... See more

Existing systems of decentralized network governance differ in two defining aspects: (1) whether rules around implementing changes to the relevant software protocols are included in the software itself; (2) the level of formalization and institutionalization of off-chain governance.

Every now and again, a few of these fragments will stick to each other and nucleate , crystallizing a substantial, synthetic analysis out of all of those bits and pieces I’ve salted into that solution of potential sources of inspiration.

When database functionality is not siloed but open, this all changes. Any app can build on the same data. No app is a gatekeeper to it. And not every app needs to build an entire siloed stack.

1. Make credible commitments