Kelli

three types of data have been used to train ML models in drug discovery. 1). Compound library and characterization data, which consists of information on drug compounds such as structure, affinity, solubility, stability, etc. 2). Molecular profiling data, which refers to omics data of biomolecules (DNA, RNA, proteins, methylation, etc) in a whole... See more

The things you learn in maturity aren’t simple things such as acquiring information and skills. You learn not to engage in self-destructive behavior. You leant not to burn up energy in anxiety. You discover how to manage your tensions, if you have any, which you do. You learn that self-pity and resentment are among the most toxic of drugs. You find... See more

When you’re working, there’s so much self-loathing. Everyone feels like their stuff is awful. When I was at CalArts I was studying painting—I’m a terrible painter—but I remember there’s a stage of a painting that just looks like a mess and then all of a sudden it becomes a painting. Movies are like that too. Magically it starts to take shape. Now I

... See more

People read nonfiction to learn and to feel. My framework for ensuring a blog post accomplishes both is to start with a first draft that focuses on "novel" ideas.

A novel idea is one that's not just new to the reader, but also significant and not easily intuited. Think of it as new and worthwhile . I've identified five categories:

• Counter-intuitive —

... See more

In the glut of generated content, no one really speaks. No one risks themselves on the page.

The conversation around taste tends to focus on what it takes to develop it, but not what it takes to use it and unlock its potential, which is confidence .

Having and developing taste is one thing, but remaining connected to our taste is another. In order to take advantage of our taste, we have to be able to access its insights and guidance, which... See more

He told me to pay attention to what I enjoyed most about my lifestyle, and try to preserve it while I experimented.