dopamine and yours

In a 2017 interview, Ev Williams (the founder of Twitter), said something that has stuck with me since: “the trouble with algorithms, is that it rewards extremes. Say you’re driving down the road and see a car crash. Of course you look. Everyone looks. The internet interprets behavior like this to mean everyone is asking for car crashes, so it... See more

Schultz suggests dopamine serves as a common currency system for desire.

The number one determinant of dopamine release is novelty.

Rather than giving us pleasure itself, as is commonly thought, dopamine motivates us to do things we think will bring pleasure. As the brain’s major reward and pleasure neurotransmitter, it’s what drives us to seek pizza when we’re hungry and sex when we’re aroused. Scientists use dopamine to measure “the addictive potential of any experience,”... See more

“The problem with things that release a lot of dopamine all at once is that our brains have to compensate. But this is really the key point — our brains don’t just then bring our dopamine firing back to baseline level,” she said. “It actually pushes dopamine levels below baseline. We go into a dopamine deficit state. That’s the way the brain... See more

Dopamine plays a lot of roles in the brain. If you kill off the cells that produce dopamine, the animal is not motivated to go out and do things. It’ll still enjoy something — like the sucrose solution you squeeze directly into its mouth — because the pleasure systems are fine. But they won’t pursue it. If you perform an action and you get more... See more

In this view, dopamine does not signify how pleasant an experience will be but how much value it has to the organism at that particular moment. Schultz notes that dopamine neurons do not distinguish among different types of reward. “They're only interested in the value,” he says. “They don't care whether it's food reward or liquid reward or money.... See more

What dopamine is “really doing,” Berridge says, “is taking things you encounter, little cues, things you smell and hear, and if they have a motivational significance, [it] can magnify that significance,” raising the incentive to pursue them. Placing dopamine directly into the nucleus accumbens of rats, he notes, will make them work two to three... See more