Organoids are self-organising, genetically stable, 3D culture systems containing both progenitor/stem and differentiated cells that resemble the tissue of origin.

Human endometrial organoids can be used to answer questions about uterine/placental cross-talk during placentation, and will provide a system for studying the pathogenesis and treatment of common conditions affecting women, such as endometriosis and endometrial cancer.

Animal models in mice and ruminants where glandular function is suppressed are unable to support implantation and pregnancy