The ratio of estrogen and testosterone determine their effects. They are mainly produced in the ovaries or testicles (and adrenals for testosterone).

Testosterone exists in free and bound form. Most of it is bound to sex hormone binding globulin (SHGB) which transport testosterone into cells and specific tissues. They control the rate of unbound testosterone. Tongat Ali and Boron seem to have a pro effect on free testosterone and estrogen and liberates bound testosterone.

As a woman who took really good care of myself my whole life, nothing aged me as much as menopause. If you are a young woman get on estradiol as early in your perimenopausal years as possible. A recent analysis of over 120 million patient records found that starting menopause hormone therapy (MHT) within 10 years of menopause (perimenopause) was... See more