potential food shortage—leptin levels are low. The relative absence of leptin’s message tells the brain, “I don’t have enough body fat!” Your brain then tells you to eat more and move less, which serves to change your behavior until your body fat is within a safer range. You become hungrier (and probably eat more), your metabolism slows down

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Ventral medial hypothalamus: control station for hunger, eating and satiety through multiple populations of neurons, which respectively control hunger and satiety.

There are endokrine signal involved to signal hunger and satiety. The archuit nucleus release chemicals that act as brakes and accelerators of hunger. - The PMOC neurons (system) produce a-MSH, which reduces appetite and get active while eating. They are activated by ultra-violate light to the eyes, which explains the lower hunger and appetite in... See more