I think everyone knows it’s possible. There’s a great Osho lecture, titled “The Attraction for Drugs Is Spiritual.” He talks about why do people do drugs (everything from alcohol to psychedelics to cannabis). They’re doing it to control their mental state. They’re doing it to control how they react. Some people drink because it helps them not care

contemplative watching of the eternal now, which is sometimes revived by the use of psychedelic drugs, but which came to me through flowers, jewels, reflected light in glass, and expanses of clear sky.