Serim Tarcan

FarmboxRx founder Ashley Tyrner, 39, sees healthy food as a form of health care. In 2014, she launched Farmbox Direct, which shipped boxes of fresh food anywhere in the U.S. In 2019, she pivoted to focus on the health care market, partnering with Medicare Advantage and private health insurance plans to offer produce boxes as a benefit to members, a... See more

We can decompose the progress in the four years from GPT-2 to GPT-4 into three categories of scaleups:

1. Compute : We’re using much bigger computers to train these models.


2. Algorithmic efficiencies : There’s a continuous trend of algorithmic progress. Many of these act as “compute multipliers,” and we can put them on a unified scale of growing

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Most people live a quietly anxious life because they know they should be doing something other than what they're doing, but they don't do anything about it because they don't know what to do, so they keep doing the same thing to numb the pain that comes with change

So, we face two bottlenecks:

Fragmented patient data that's hard to find, reconcile, and trust.

Documentation burden that spills into after-hours work and fuels burnout.

Both undermine our ability to deliver high-quality care and succeed in value-based models.

Every act of conscious learning requires the willingness to suffer an injury to one's self-esteem.

That is why young children, before they are aware of their own self-importance, learn so easily; and why older persons, especially if vain or important, cannot learn at all.

The Arctic is warming four times faster than the world at large, causing ice to shrink by an area the size of Austria each year. Since the 1980s the volume of ice has fallen by 70% or more. The Arctic’s first ice-free day may occur before 2030.

A framework for evaluating opportunities in digital health

Here are some of the diligence questions I have collected over the years, that I share with my students. They are broken down into categories of risk: Market, Execution, and Product. 

Market risk

At a high-level, does this address a real problem in healthcare (cost, quality, access)

Is there a... See more

the hope lies with the Arctic’s “green” minerals, which global warming is making more accessible. They include cobalt, graphite, lithium and nickel, important ingredients in electric-car batteries; zinc, used in solar panels and wind turbines; copper, required for all sorts of things electric; and rare earths, crucial to many types of green and... See more

Finding your way in life is like unlocking the combination of a safe. You have to go forwards and backwards. Life is not a direct march from A to B. The twists and turns are progress, not regression. What feels like a setback in the moment is later revealed to have been part of the path all along. Each move was necessary to get to your end goal.