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These advances have not come easily. Scientists cannot simply treat E. coli as a machine. The microbe is a living thing, and it responds to manipulation in unexpected ways.
Carl Zimmer • Microcosm: E. coli and the New Science of Life
RNA interference operates by deploying an enzyme known as “Dicer.” Dicer snips a long piece of RNA into short fragments. These little fragments can then embark on a search-and-destroy mission: they seek out a messenger RNA molecule that has matching letters, then they use a scissors-like enzyme to chop it up. The genetic information carried by that
... See moreWalter Isaacson • The Code Breaker
J’y ai fait la rencontre d’un capitaine de corvette de la famille d’Honoré d’Estienne d’Orves, qui, un jour, au mont Valérien, m’a décrit Paris comme « la Grande Broyeuse ». Je crois que c’est de cette expression exacte que m’est venue la passion de l’humanisme neuronal. Aucune formule ne m’avait paru jusque-là condenser aussi clairement la
... See moreIdriss Aberkane • Libérez votre cerveau ! (REPONSES) (French Edition)
Beadle and Tatum now created bread mold mutants. Some were unable to produce certain types of amino acids because they now lacked a key enzyme.
Carl Zimmer • Microcosm: E. coli and the New Science of Life
The ribosome is your turntable, the mRNA is the vinyl LP record, and the protein is the music you hear when you lower the needle.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
when the temperature is cool, E. coli is constantly reading the gene for sigma 32 and making RNA copies. But at normal temperatures the RNA folds in on itself, and so E. coli cannot use it to make a protein. At normal temperatures the microbe is loaded with sigma 32 RNA but no actual sigma 32 protein.
Carl Zimmer • Microcosm: E. coli and the New Science of Life
Cognitive Science
Matthew Sparks • 1 card
Pourquoi les bactéries ? Pourquoi pas les singes ou les poissons ? – Il voulait comprendre la cellule à son stade le plus primaire. Pour lui, l'homme n'étant qu'un conglomérat de cellules, il fallait comprendre à fond la « psychologie » d'une cellule pour déduire le fonctionnement de l'ensemble. « Un gros problème complexe n'est en fait qu'une
... See moreBernard Werber • Les Fourmis (French Edition)
and natural selection rewired its network. One of the simplest means by which E. coli’s network can be rewired is the accidental duplication of a chunk of DNA. In some cases, the duplication may create two copies of the same switch. If the gene for one of those switches mutates, it may begin to control a different gene. In other cases, extra copies
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