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Mercer_Pub 248
The study describes the development of a continuous evolution system to engineer small degron tags that can be inserted into endogenous genes and selectively degrade proteins using specific small molecules.
LinkI’m sharing the following details that may be useful to you:
(1) Plasmid Full Name:
pTRE3GBi_EF1A_Tet3G_IRES_Puro-VHH hFBXW11-mCherry
or pTRE-BI-hGRAD
> Bacterial Resistance: Ampicillin.
> Addgene Link: https://www.addgene.org/207837/
(2) Reference Paper:
https://rupress.org/jcb/article/223/2/e202304030/276463/hGRAD-A-
... See more
List of approved Gene Therapies
**best selling is ZOLGENSMA w/ 2021 ~$1.4B Revs https://t.co/fsNh706DHv
- YouTube
youtube.comNew Blueprint therapy
Three peptides for thymus rejuvenation, telomere lengthening & epigenetic age slowing/reduction. Therapy showed a 66% all-cause-mortality risk reduction from 6 years of usage.
Intramuscular injection, 10 mg daily for 5 days every 6... See more
Bryan Johnsonx.comNetwork analysis of TCGA and GTEx gene expression datasets for identification of trait-associated biomarkers in human cancer
Protocols for analyzing TCGA and GTEx RNA-Seq data to identify trait-associated biomarkers in human cancer, including differential expression, network analysis, and survival analysis methods.
pmc.ncbi.nlm.nih.govgenomics
Abhijeet Patra • 1 card