Sublime

Oxidized LA metabolites (OXLAMs) drive systemic oxidative stress — When LA is heated, stored, or metabolized in excess, it forms OXLAMs, damaging breakdown products that are biologically active. OXLAMs like 4-hydroxynonenal (4-HNE) are generated during lipid peroxidation and damage DNA, proteins, mitochondria, and even stem cells. These oxidized by... See more

Stored LA contributes to mitochondrial injury — Mitochondria use a special fat called cardiolipin to help generate energy. As LA dominates the diet, it becomes a major building block of cardiolipin, making it fragile and prone to oxidation. The result is impaired energy production, increased oxidative stress, and higher vulnerability to chronic dis... See more