The town of La Mesilla is located near Las Cruces along the Rio Grande. During the 1850s, 1860$, and 1870s, Mesilla was one of the most, important towns in southern : New Mexico. However, in 1881 the Santa Fe Railroad.went through the adjacent town of Las Cruces, which eclipsed La Mesilla as the major town in the area. Because the Community of: La... See more