Juan Orbea

Information moves, or we move to it. Moving to it has rarely been popular and is growing unfashionable; nowadays we demand that the information come to us. This can be accomplished in three basic ways: 1) moving physical media around, 2) broadcasting radiation through space, and 3) sending signals through wires. This article is about what will, for... See more

And reset they must. When you look at how much median valuations were driven up in the past 5 years alone it’s bananas. Median valuations for early-stage companies tripled from around $20m pre-money valuations to $60m with plenty of deals being prices above $100m.

3) Pushing against regulatory conservatism in general, by increasing the chance that there's some jurisdiction that will let you do any particular thing. Allowing people to opt into network states that accept higher levels of risk could be a successful strategy for pushing against this.

In short, VCs in these frontier domains essentially need multiple miracles for these companies to succeed. Compare those scale up challenges to traditional biotech and pharma, where the entire industry has designed systems and processes to prove safety and efficacy and grow production. There’s still serious technical risk, but it’s knowable... See more

Crossroad #4 – First JobThe professional relationships you form during your first job are the seed of your professional network which influences the arc of your career — from how you think about work, to how you’re known, to the geography where you have advantaged job access for a long time.

Chris Olah has had a fascinating and unconventional career path.

Feral Type – its niche is narrative and society. Narrative becomes reality. This gives rise to 2 failure conditions: 1) delusion (which is an identification with an ideology that takes the story as actually being reality) and 2) deception (the perception of society being first and foremost a hierarchy/conflict between domesticated people).