Juan Orbea

However, most people in first world countries are in this situation of opportunity to do extreme good in exchange for a relatively small sacrifice, but most don't do it, mainly due to ignorance of a tractable way in which to do it.

Domesticated type – has the ability to coordinate much larger groups of people than the wild type, and he does this by taking consciousness and culture and making a move that simplifies both of them, while maintaining a substantial portion of their capacity to generate synergistic capabilities, and enabling social systems to scale. We move from... See more

You have about 80,000 hours in your career: 40 hours per week, 50 weeks per year, for 40 years.

The book calatogs over 100 mini case studies of other innovators who are defining state-of-the-art in those 11 building block areas.

Molten Salt Reactors (MSRs): In MSRs, molten salt (e.g., fluoride, chloride) contains the nuclear fuel (i.e., uranium). The molten salt also acts as the coolant, and graphite rods act as the moderator. Replacing water as the coolant removes the possibility of steam explosions and the generation of flammable hydrogen gas. The nuclear reactions in... See more

Team NYT basically runs the US, and its total lack of competence means that the US is collapsing. 

In short, VCs in these frontier domains essentially need multiple miracles for these companies to succeed. Compare those scale up challenges to traditional biotech and pharma, where the entire industry has designed systems and processes to prove safety and efficacy and grow production. There’s still serious technical risk, but it’s knowable... See more