Johanna

Software entrepreneur Ray Ozzie has a specific technique for handling potential interruptions — the four-hour rule. When he’s working on a product, he never starts unless he has at least four uninterrupted hours to focus on it. Fractured blocks of time, he discovered, result in more bugs, which later require fixing.

The best way to be good at sales is to genuinely believe in what you’re selling. Selling what you truly believe in feels great, and trying to sell snake oil feels awful.

What the Fed is actually trying to do here—as opposed to the story it’s telling about what’s happening in the economy—is clear, yet extremely difficult: It is trying to destroy demand just enough to reduce excess inflation but not so much that the economy crashes. This a little bit like trying to tranquilize a raging grizzly bear with experimental... See more

Funding agencies need to stop funding under-powered studies using sloppy statistical methods and small group sizes. This will mean that fewer groups will receive funding. However, without some pain there will be no improvement. Labs should be forced to adapt to a harsh new reality that they will only get funding if they conduct high powered,... See more

One of the best ways to build a network is to develop a reputation for really taking care of the people who work with you. Be overly generous with sharing the upside; it will come back to you 10x. Also, learn how to evaluate what people are great at, and put them in those roles.

I think that the perception of stagnation in science – and in biology specifically – is basically fake news, driven by technological hedonic treadmill and nostalgia. We rapidly adapt to technological advances – however big they are – and we always idealize the past – however terrible it was.

Few recruiting messages are as powerful (when true) as “the world needs this, it won’t happen any time soon if we don’t do it, and we are much less likely to succeed if you don’t join.”

If the metrics of Universal Basic Mobility are successful and felt equitably, then UBM should in theory stimulate cities to evolve around them in the same way they did for the car. Think tree canopied scooter and bike lanes on every block. Buses that are so perfectly synched with your cycle, you never clock waiting. Mini Buses that arrive at your... See more