Johanna

In order to improve allocation, we should pay attention to funding models. We may want to improve the models we have, or reallocate our portfolio of them, or bring back old ones that we have left behind, or invent new ones.

When we cut off the supply and discovery of new drugs, it’s like outlawing the electric motor or the idea of a randomized controlled trial. Without drugs, modern people have stopped making scientific and economic progress. It’s not a dead stop, more like an awful crawl. You can get partway there by mixing redbull, alcohol, and sleep deprivation,... See more

The problem with most management, leadership, and business books is that many of them harp on the same self-evident points, overconfident in the usefulness of their prescriptions for would-be imitators. They tend to vastly underestimate the role of circumstance, luck, the nature of completion, and the effects of scale, among other things.

Excessive concern about low levels of radiation led to a regulatory standard known as ALARA: As Low As Reasonably Achievable. What defines “reasonable”? It is an ever-tightening standard. As long as the costs of nuclear plant construction and operation are in the ballpark of other modes of power, then they are reasonable.This might seem like a... See more

Scientists often bemoan the state of originality in their field. New ideas are getting “harder to find.” Progress in large fields of science and technology is “slowing down.” Scientific knowledge has been in “clear secular decline.” (One wonders about the originality of their bemoaning.) But today’s researchers aren’t getting worse at coming up... See more

Mechanization doesn’t require replicating a human’s movement exactly. The greatest gains from mechanization occur when a complex human movement can be replaced with a simple mechanical movement. A ship’s propeller doesn’t move the same way a fish’s tail fin does - it replaces the back and forth movement of the tail with a simple rotation that... See more

Their motivations are often more complex than they seem—specifically, they are frequently very driven by genuine curiosity.

Transportation equity is not a discrete problem. It poses a barrier to accessing everything that constitutes a good quality of life; healthcare, fresh food, public Wi-Fi, friends, education, jobs, and voting. If everything is brought within a 15 minute radius, not only does car ownership become widely unnecessary, prompting the provision of a... See more