Johanna

Small sample sizes. We also need to know that the study was big enough to justify the claims made. For example, it’s pretty obvious that men are on average taller than women. But to have a good chance of detecting this difference in an experiment, you’d need at least 20 people to find a statistically significant result. Unfortunately, such huge... See more

I have tried all the models described. Personally, I’d recommend you avoid hybrid approaches and act as distributed as possible - or just don’t do remote at all and be co-located. Both are fine.

Jargon hides our lack of understanding. When forced to write out an idea from start to finish in simple language, you discover where you struggle … where it doesn’t quite make sense … where you get frustrated … where you don’t really understand as well as you thought. Only by identifying gaps in your knowledge can you fill them. 

I’ve learned that I can’t be very productive working on things I don’t care about or don’t like. So I just try not to put myself in a position where I have to do them (by delegating, avoiding, or something else). Stuff that you don’t like is a painful drag on morale and momentum.

If you do not work on an important problem, it's unlikely you'll do important work. It's perfectly obvious. Great scientists have thought through, in a careful way, a number of important problems in their field, and they keep an eye on wondering how to attack them. (...) By important I mean guaranteed a Nobel Prize and any sum of money you want to... See more

The picture this survey paints is bleak: Over the past century, we’ve vastly increased the time and money invested in science, but in scientists’ own judgement, we’re producing the most important breakthroughs at a near-constant rate. On a per-dollar or per-person basis, this suggests that science is becoming far less efficient.

If you want an average successful life, it doesn’t take much planning. Just stay out of trouble, go to school, and apply for jobs you might like. But if you want something extraordinary, you have two paths:1. Become the best at one specific thing.2. Become very good (top 25%) at two or more things.