Johanna

The very worst kind of manager is the one who feels threatened by his team. Consciously or not, he is afraid of those who are "the very best", so he consistently staffs his team with people who will not challenge him.

Invention is easily overrated, and implementation is often underrated.

academia has a lot of problems and it could work much better. However, these problems are not as catastrophic as an outside perspective would suggest. My (contrarian, I guess) intuition is that scientific progress in biology is not slowing down. Specific parts of academia that seem to be problematic: rigid, punishing for deviation, career... See more

Hiring is all about probabilities. When we evaluate a candidate, we are basically just trying to predict whether that candidate will be a success in the position being filled. We're trying to know the future, but we have no prophets and no Oracle.

Let me summarize. You've got to work on important problems. I deny that it is all luck, but I admit there is a fair element of luck. I subscribe to Pasteur's ``Luck favors the prepared mind.'' I favor heavily what I did. Friday afternoons for years - great thoughts only - means that I committed 10% of my time trying to understand the bigger... See more

Economic growth is not objectively good by itself. But part of the question here is, “what happened to economic growth around 1970?” When the companies in the global #1 and #2 positions were both founded by people who used LSD, it makes you want to pay attention. It makes you wonder what Jeff Bezos, Larry Page, and Sergey Brin might have tried... See more

You can create value with breakthrough innovation, incremental refinement, or complex coordination. Great companies often do two of these. The very best companies do all three.