Johanna

To show how this might work, let’s take multiple sclerosis as an example. It is a devastating condition in need of better therapies. When testing new drugs in animal studies, researchers measure and report a number of different metrics, including the effects of drug candidates on inflammation, on damage to nerve fibres (axon loss), on damage to the... See more

I have tried all the models described. Personally, I’d recommend you avoid hybrid approaches and act as distributed as possible - or just don’t do remote at all and be co-located. Both are fine.

In order to improve allocation, we should pay attention to funding models. We may want to improve the models we have, or reallocate our portfolio of them, or bring back old ones that we have left behind, or invent new ones.

This is the fundamental tension: culture vs. math. 1. Management has clearly and consistently shown a greater preference for offices than workers. vs 2. During a downtown, it’s clearly advantageous for zombie-office companies to reduce their footprint

All of these lines of evidence lead me to the same conclusion: constant growth rates in response to exponentially increasing inputs is the null hypothesis. If it wasn’t, we should be expecting 50% year-on-year GDP growth, easily-discovered-immortality, and the like.