Johanna

Critically, we need to be much more strategic in the way we use published research findings (from the lab) to inform what we do next (e.g. clinical trials). We need to combine and integrate — systematically — the full granularity of research claims and their provenance to provide a richness of detail to our understanding. This process of... See more

Throughout my career I’ve noticed that when I work about 4-5 hours on something, I’m done. Regardless of whether I’ve allocated 6 or 8 or 10 hours to it, I either finish my tasks, or I run out of runway to finish them. Most of the time spent after that is just obsessive tweaking.

Don’t ask around about the person before you interview them; and never, ever talk to the other interviewers about the candidate until you’ve both made your decisions independently. That’s the scientific method.

Somewhat counterintuitively, also try looking at communities that are passionately dissatisfied with the status quo in your field or industry. It might be harder to state your case, but if you reach out to the right people, you can explain that your product is the one they have been waiting for in the market. They will be immediately and urgently... See more

One other thing about meetings in remote companies: working remotely has made me realize how unimportant and ritualized so many meetings are. Often times, I will get 90% of the way through scheduling a meeting in Google Calendar only to ask myself “can’t we just update each other on this project throughout the week via Slack?” Even staff meetings... See more

To “hire slow, fire fast,” start by being absurdly selective in who you hire.

There is no evidence that sleep was universally segmented, and there is also little evidence that segmented sleep is better. A 2021 meta-analysis of studies on biphasic sleep schedules found that segmented-sleeping subjects actually reported “lower sleep quality … and spent more time in lighter stages of sleep.” One reasonable takeaway is that... See more

You should trade being short-term low-status for being long-term high-status, which most people seem unwilling to do.