Johanna

When we cut off the supply and discovery of new drugs, it’s like outlawing the electric motor or the idea of a randomized controlled trial. Without drugs, modern people have stopped making scientific and economic progress. It’s not a dead stop, more like an awful crawl. You can get partway there by mixing redbull, alcohol, and sleep deprivation,... See more

If you criticize X to Y, Y wonders whether you criticize him to others as well. This problem can increase to the extent your criticism is biting and on the mark.

A model is a simplification which fosters understanding.

In the pandemic, we (at first) didn’t have enough masks or tests, then we didn’t have enough vaccines or pills. We don’t have enough homes, immigrants, doctors, or microchips. We’re not lacking in scientific breakthroughs. The U.S. is languishing because many of our policies are designed for scarcity. What we need is the opposite: an abundance... See more

In order to improve allocation, we should pay attention to funding models. We may want to improve the models we have, or reallocate our portfolio of them, or bring back old ones that we have left behind, or invent new ones.

Research publications are some of the world’s most important repositories for content and information ever created. They tie ideas and findings together across time and disciplines, and are forever preserved by a network of libraries. They are supported by evidence, analysis, expert insight, and statistical relationships. They are extremely... See more