Joey DeBruin
@joeydebruin
Helping communities build public knowledge online. Founder @withBackdrop. Past/current product/advisory roles @Benchling @ResearchGate @Forefront__ @SeedClub
Joey DeBruin
‘I think it is actively happening’: Is Boston’s biotech industry doomed? - The Boston Globe
bostonglobe.com
Pen and paper took us as far as the moon. It's about time we went to the stars.
Oliver Hunt • Building a 21st century interface for science
There is no ideal pitch deck. The narrative depends on what you’re building—but I really like this one: 1. Vision for the world in 5 years 2. The novel wedge that will get you there 3. How you plan to distribute it 4. What could go wrong 5. What you’ll prove by the time you need…
Nikita Bierx.comLet’s say Farcaster, or other Web 3 social media like it, wants to run ads for the free version of the product. Rather than going out and building an entire ads system (as Facebook and every other social media publisher had to), they can use the composability and permissionlessness of Web 3 to spin up monetization quickly. Assuming an attribution... See more
Antonio Garcia Martinez • Everything is an ad network
The downside of lead generation businesses is that they can be a race to the bottom if they're in a crowded and competitive market. The barriers to entry are essentially aggregating supply (i.e. buyers of leads or businesses willing to pay for new customers) so there is little in the way of defensibility. The other downside is that they are very... See more
Marketplaces, Lead Generation, and Brokerages
Vertical integration is typically the dominant strategy when industries are in their early stages or undergoing significant transformation, when market structures are unclear, supply chains are underdeveloped, and new technologies are emerging. Companies that can control more of the value chain can introduce new products that the market needs... See more
Packy McCormick • Vertical Integrators: Part II
I don’t think ‘public utility’ is the most useful metaphor to understand what Twitter and its peers actually are.Public utilities make sense when the product is a simple commodity, essential for everyday life, and delivered through a set of pipes that are incredibly expensive to install and maintain.
every.to • Twitter as a City-State
That right there is the recipe for genuine innovation:
- Embrace uncertainty and the fact one doesn’t know the future.
- Understand that people are inventing things — and not just technologies, but also use cases — constantly.
- Remember that the art comes in editing after the invention, not before.