dopamine and yours

What dopamine is “really doing,” Berridge says, “is taking things you encounter, little cues, things you smell and hear, and if they have a motivational significance, [it] can magnify that significance,” raising the incentive to pursue them. Placing dopamine directly into the nucleus accumbens of rats, he notes, will make them work two to three... See more

Dopamine plays a lot of roles in the brain. If you kill off the cells that produce dopamine, the animal is not motivated to go out and do things. It’ll still enjoy something — like the sucrose solution you squeeze directly into its mouth — because the pleasure systems are fine. But they won’t pursue it. If you perform an action and you get more... See more

Rather than giving us pleasure itself, as is commonly thought, dopamine motivates us to do things we think will bring pleasure. As the brain’s major reward and pleasure neurotransmitter, it’s what drives us to seek pizza when we’re hungry and sex when we’re aroused. Scientists use dopamine to measure “the addictive potential of any experience,”... See more

In a series of experiments begun in the 1980s, Schultz and his colleagues showed that when monkeys first get something pleasant—in this case, fruit juice—their dopamine neurons fire most intensely when they drink the liquid. But once they learn that a cue like a light or a sound predicts the delivery of delicious stuff, the neurons fire when the... See more

“Often, depressed people say they don’t want to go out with their friends,” says Salamone. But it’s not that they don’t experience pleasure, he says – if their friends were around, many depressed people could have fun.

“Low levels of dopamine make people and other animals less likely to work for things, so it has more to do with motivation and... See more

Our dopamine economy, or what historian David Courtwright has called “limbic capitalism,” is driving this change, aided by transformational technology that has increased not just access but also drug numbers, variety, and potency.

The number one determinant of dopamine release is novelty.

In a 2017 interview, Ev Williams (the founder of Twitter), said something that has stuck with me since: “the trouble with algorithms, is that it rewards extremes. Say you’re driving down the road and see a car crash. Of course you look. Everyone looks. The internet interprets behavior like this to mean everyone is asking for car crashes, so it... See more