Final version is out: aging as the result of loss of goal-directedness https://t.co/Vmm2zFQHzu @BeneHartl @LPiolopez "Although substantial advancements are made in manipulating lifespan in model organisms, the fundamental mechanisms driving aging remain... See more

Overview of the ALS drug pipeline from a nice recent review. Authors note "approaches that are under-represented, based on current knowledge of the pathophysiology of ALS, include those targeting mitochondrial dysfunction and proteostasis" source: https://t.co/Szidtj6Luv https://t.co/e85fU5GzWz