To show how this might work, let’s take multiple sclerosis as an example. It is a devastating condition in need of better therapies. When testing new drugs in animal studies, researchers measure and report a number of different metrics, including the effects of drug candidates on inflammation, on damage to nerve fibres (axon loss), on damage to the... See more

While animal models of endometriosis are important to study the establishment, progression, and regression of endometriosis via the surgical induction of disease (Bruner et al. , 1995; Grümmer, 2012; Burns et al. , 2025; Dodds et al. , 2025; Hull et al. , 2025), most of these experimental animals do not naturally develop this disease and limit... See more