How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence

Hubbard believed it was unethical to profit from LSD, which led to tensions between him and some of the institutions he worked with, because they were charging patients upwards of five hundred dollars for an LSD session. For Hubbard, psychedelic therapy was a form of philanthropy, and he drained his fortune advancing the cause.

“problem solving in engineering always involves irreducible complexity. You’re always balancing complex variables you can never get perfect, so you’re desperately searching to find patterns. LSD shows you patterns.

“People don’t realize how few tools we have in psychiatry to address existential distress.” Existential distress is what psychologists call the complex of depression, anxiety, and fear common in people confronting a terminal diagnosis. “Xanax isn’t the answer.” If there is an answer, Bossis believes, it is going to be more spiritual in nature than

Richards emerged from those first psychedelic explorations in possession of three unshakable convictions. The first is that the experience of the sacred reported both by the great mystics and by people on high-dose psychedelic journeys is the same experience and is “real”—that is, not just a figment of the imagination. “You go deep enough or far ou

Patrick talked about his body and cancer “as [a] type of illusion.” It also became clear that, psychologically at least, Patrick was doing remarkably well in the aftermath of his session. He was meditating regularly, felt he had become better able to live in the present, and “described loving [his] wife even more.” In a session in March, two months

“A high-dose psychedelic experience is death practice,” says Katherine MacLean, the former Hopkins psychologist. “You’re losing everything you know to be real, letting go of your ego and your body, and that process can feel like dying.” And yet the experience brings the comforting news that there is something on the other side of that death—whether

But to the extent that the upheaval of the 1960s was the result of an unusually sharp break between generations, psychedelics deserve much of the blame—or credit—for creating this unprecedented “generation gap.” For at what other time in history did a society’s young undergo a searing rite of passage with which the previous generation was utterly u

If you need to be reminded how completely mental habit blinds us to experience, just take a trip to an unfamiliar country. Suddenly you wake up! And the algorithms of everyday life all but start over, as if from scratch. This is why the various travel metaphors for the psychedelic experience are so apt. The efficiencies of the adult mind, useful as

I have no memory of ever having exhaled, or of being lowered onto the mattress and covered with a blanket. All at once I felt a tremendous rush of energy fill my head accompanied by a punishing roar. I managed, barely, to squeeze out the words I had prepared, “trust” and “surrender.” These words became my mantra, but they seemed utterly pathetic, w

The myriad new connections that spring up in the brain during the psychedelic experience, as mapped by the neuroimaging done at Imperial College, and the disintegration of well-traveled old connections, may serve simply to “shake the snow globe,” in Robin Carhart-Harris’s phrase, a predicate for establishing new pathways. Mendel Kaelen, a Dutch pos