The Impending VR Moment

The iPhone didn’t happen in a vacuum. Apple needed to learn to make low-power devices with the iPod; flash memory needed to become viable at an accessible price point; Samsung needed to make a good enough processor; 3G networking needed to be rolled out; the iTunes Music Store needed to provide the foundation for the App Stor... See more

GLP-1s are master signals that governs the body's state of being either well-fed or starving. This signal influences numerous bodily processes, including metabolism, inflammation, and reward systems. This broad influence on these fundamental processes may explain why GLP-1s appear to be effective across so many conditions.

Having this vessel that you’re motivated to fill encourages being more observant and analytical in daily life too.

Market Selection in Vertical Integration

If you were to ask what sunk Convoy, it ultimately boils down to an over-dependence on the digital freight matching software they pioneered with a corresponding inattention to the operational parts of the brokerage that were really low margin. Technology isn’t a panacea for operational excellence. Every vert... See more

He thought about space the way he thought about mathematics or analytic philosophy or the Torah or Mozart’s twentieth piano concerto, which he sometimes played at night when my sister and I were going to bed. It was beautiful and complex and infinite, and how could you not want to explore that, know where it came from, know where we came from?

QUOTE OF THE DAY:

"Fiction reveals truths that reality obscures.”

-Jessamyn West (American author)

It also could not be a better time for a paradigm shift. AGI and likely soon after superintelligence will force us to rethink human role in society. In the new world, the value of the human brain is increasingly defined on how creative it can be. Cosmic optimism helps us navigate this transformation by emphasizing focus on the very human qualities ... See more

Patient-Directed Care

Circling around all of this continues to be a more fundamental shift of how people are paying attention to biology and their own health.

While patient-directed care broadly is an increasingly consensus trend (borne out of the rise of the quantified self of yesterday and a large number of growing podcasters/authors today) the nua... See more