The generic drug supply chain sprawls across the globe and is pretty opaque. Manufacturers are required to report to the FDA when there’s a disruption that could impact supply, but the details aren’t always shared with the public and can be protected as proprietary information

paradox with generic injectables in particular: an intensive manufacturing process with very low profit margins.

In an FDA analysis of 163 drugs in shortage from 2013 to 2017, generic sterile injectables made up roughly half of the sample

Only about 30% of API manufacturing facilities that supply ingredients for drugs for the US market are themselves based in the US. The rest are spread across places like India, China, and the EU

Finding your way in life is like unlocking the combination of a safe. You have to go forwards and backwards. Life is not a direct march from A to B. The twists and turns are progress, not regression. What feels like a setback in the moment is later revealed to have been part of the path all along. Each move was necessary to get to your end goal.

“Most people are interested. Few are truly committed.

Interested people act when it's convenient; committed people act no matter what. Interested people do the minimum; committed people push beyond limits. Interested people wait to be told; committed people take the initiative.

Fully committing is the key to accomplishment.”

Poet Emily Dickinson on the value of small actions:

"If I can stop one heart from breaking,

I shall not live in vain;

If I can ease one life the aching,

Or cool one pain,

Or help one fainting robin

Unto his nest again,

I shall not live in vain."

Source: "If I Can Stop One Heart From Breaking"

There’s a famous WWI poem about how one generation sacrifices for another, hopes that they can carry the work onwards. “To you from failing hands we throw,” it reads, “The torch; be yours to hold it high.”

FarmboxRx founder Ashley Tyrner, 39, sees healthy food as a form of health care. In 2014, she launched Farmbox Direct, which shipped boxes of fresh food anywhere in the U.S. In 2019, she pivoted to focus on the health care market, partnering with Medicare Advantage and private health insurance plans to offer produce boxes as a benefit to members, a... See more