Sublime
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cutting-edge research into a biological function.
James Nestor • Breath: The New Science of a Lost Art
The longevity genes I work on are called “sirtuins,” named after the yeast SIR2 gene, the first one to be discovered. There are seven sirtuins in mammals, SIRT1 to SIRT7, and they are made by almost every cell in the body. When I started my research, sirtuins were barely on the scientific radar. Now this family of genes is at the forefront of medic... See more
David A. Sinclair, Matthew D. LaPlante • Lifespan: Why We Age—and Why We Don't Have To

A strong grip is a reliable indicator of your potential for a longer, healthier, independent life. Read more here 💪
Patrick Dalesubstack.comImagine your body is made of clay, with each type and frequency of movement shaping the physical outcome. Take your imaginary body-ball-of-clay through your personal movement timeline, considering your early development, favorite activities, accidents or sports injuries, footwear habits, the desks at school, your favorite couch, and driving posture
... See moreKaty Bowman • Move Your DNA: Restore Your Health Through Natural Movement
Last week, @chamath and I had dinner. He had this to say:
"Bryan's skin is incredible. His skin is like a porcelain dolls. Both my wife and I were like, we've never seen skin like this. It's incredibly soft. It's the softest skin I've ever touched in my life."
Supple skin is proof of young... See more
Bryan Johnsonx.com
it is the most fundamental act of our species: to sustain the body until time leaves it behind.
Ocean Vuong • On Earth We're Briefly Gorgeous
This is why I insist my patients undergo a DEXA scan annually—and I am far more interested in their visceral fat than their total body fat.