Sublime

cycling between wet and dry conditions allowed all four nucleotides to accumulate essentially in one pot.

unusual set of Tetrahymena genes that existed as minichromosomes, each less than a thousandth the size of the smallest human chromosome. These individual DNA molecules harbored Tetrahymena’s ribosomal RNA genes.

proteins that allow double-stranded RNA to silence gene expression.

they wanted it to use the sequence of A, G, C, and U nucleotides to predict the correct 3D structure.

The purpose of studying the ribosome was to understand protein synthesis, and, as we’ve already learned, the ribosome doesn’t make protein all by itself. It needs mRNA to specify which protein gets made, and it needs tRNAs to bring in the matching amino acids.

day followed night

the uncut DNA could be cut simply by designing a new guide RNA to match 20 nucleotides of its sequence.