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Gene Machine: The Race to Decipher the Secrets of the Ribosome


BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.” https://t.co/gYrdFFcD4T
One of them was an enzyme, appropriately anointed Dicer,
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
positively charged magnesium ions, which are normal constituents of living cells, positioned themselves to solve the charge-repulsion problem of folding a highly negatively charged RNA.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
Remarkably, about half of all useful antibiotics target bacterial ribosomes.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
interference (RNAi).
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
ribozyme, a ribonucleic acid with enzymatic activity.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
ribosomal RNA (rRNA)