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RNA indeed had information and function in the same molecule!
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
The original version, the one shown in Equation 4.1, is based on the existence of a prebiotic form of RNA capable of self-replication, a sr-RNA.
Pier Luigi Luisi • The Emergence of Life: From Chemical Origins to Synthetic Biology
RNA, conversely, doesn’t have one shape but millions of possible shapes.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
U6 enters the scene tightly entwined with U4, and together they find their place on the intron. But then U2 butts in, stealing away U6, and U4 exits the stage in a huff. Now U6 and U2, with some help from U5, are free to produce the chemistry needed to complete the splicing reaction. Together they act as a ribozyme, catalyzing the mRNA splicing pro
... See moreThomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
Interspaced with these repeats were snippets of sequence that, it emerged, came not from bacteria but rather from phages, the viruses that attack them. It seemed that the bacteria were keeping track of previous encounters with invading phages. The repeats were later found to direct the insertion of new phage sequences into the array, akin to updati
... See moreThomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
Neupath
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