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ribozymes catalyze a series of reactions, including polymerizations
Pier Luigi Luisi • The Emergence of Life: From Chemical Origins to Synthetic Biology
The idea was to short-circuit the production of a protein by introducing an RNA that was complementary (“antisense”) to its mRNA. The antisense strand would base-pair with the mRNA of interest, covering up the codons and preventing protein synthesis.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
An effective antibiotic needs to disrupt a vital bacterial process without affecting related human processes.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
One of them was an enzyme, appropriately anointed Dicer,
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
makes its entrance. The
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
and the particular enzyme that cuts the unwanted extra sequences preceding a tRNA is called ribonuclease P (RNase P). P is for processing.
Thomas R. Cech • The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
Decoding Digital Culture with Science Fiction: Hyper-Modernism, Hyperreality, and Posthumanism
RNA by itself is too unstable to be a good drug; it’s easily degraded by the ribonucleases that are abundant in all human tissues because they break down RNA present in the food we eat or allow cells to switch their pattern of gene expression.