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I’m sharing the following details that may be useful to you:
(1) Plasmid Full Name:
pTRE3GBi_EF1A_Tet3G_IRES_Puro-VHH hFBXW11-mCherry
or pTRE-BI-hGRAD
> Bacterial Resistance: Ampicillin.
> Addgene Link: https://www.addgene.org/207837/
(2) Reference Paper:
https://rupress.org/jcb/article/223/2/e202304030/276463/hGRAD-A-
... See more
Ok this paper is bonkers and I love it https://t.co/uWQzQmRKKw https://t.co/OLTskgkEAn
At first I didn't realize how big this was, until I read the fine print: TLDR with the insights baked in:
OpenAI has developed a novel language model called GPT-4b micro, specifically designed for protein engineering in collaboration with Retro Biosciences, a longevity research company backed by Sam Altman's $180... See more
David Shapiro ⏩x.comA matter of choice: People and possibilities in the age of AI
The 2025 Human Development Report explores the intersection of artificial intelligence and human development, emphasizing the importance of people's choices in shaping equitable outcomes amid technological advancements.
hdr.undp.org
Mercer_Pub 248
The study describes the development of a continuous evolution system to engineer small degron tags that can be inserted into endogenous genes and selectively degrade proteins using specific small molecules.
Link
AI for Proteins is moving from sequence-only to structure-function-aware protein generation.
In case you missed it this weekend, meet APM from two ByteDance interns:
The first generative model that can directly design multi-chain protein complexes at the all-atom level
Pretrained model on protein sequences using a masked language modeling (MLM) objective. It was introduced in
this paper and first released in
this repository. This model is trained on uppercase amino acids: it only works with capital letter amino acids.
Model description
ProtBert is based on Bert model which pretrained on a large corpus of protein... See more
this paper and first released in
this repository. This model is trained on uppercase amino acids: it only works with capital letter amino acids.
Model description
ProtBert is based on Bert model which pretrained on a large corpus of protein... See more
Rostlab/prot_bert · Hugging Face
The results are out! Damn 153 characterized but only 5 bind coming just from 3 groups/persons! https://t.co/zK4P27jhbG