Sublime
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For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug

Labcorp quietly entered the longevity testing game.
Their new Whole Health panel covers 1,000+ biomarkers—similar to what startups like Function & Superpower offer, but DTC.
As labs make these moves, the value will shift to interpretation, care, and outcomes. https://t.co/4kEoQoxgst
GLP1s have added $1T in market cap to Eli and Novo over the last 5 years. That's 3x+ the market cap created by all biopharma startups over the last 30 years combined. This is a bit of an indicment of the biotech startup ecosystem. There are many $1T and even $10T drugs to be invented, we just don't fund them. Through no one persons fault, the... See more
Blake Byersx.com
This is Jeff Yan.
He is the co-founder of Hyper Liquid, doing $10B in daily volume.
He went from being a quant at Hudson River Trading to running one of the largest decentralized exchanges in crypto.
Here's what you need to know: https://t.co/eZeRmKQ06g
Today’s guest, Andrew Milgram, spent $600M buying NYC taxi medallions at the peak of Uber's power—an investment which gives you a sense of Andrew’s style.
He describes a “K-shaped economy,” where one small group of companies does incredibly well while the rest struggle.
Amidst it all he... See more
Patrick OShaughnessyx.com

Antonio Gracias on investing in companies that benefit from choas https://t.co/LbAjX3DMbt

After 2+ years heads down, I'm thrilled to unveil what I've been building with @aryelipman! @biosphereio, we're unleashing biomanufacturing with a breakthrough UV-sterilized reactor that will slash the cost of producing abundant and sustainable chemicals and food at world scale. We're backed by $8.8m in financing led by @lowercarbon and VXI, with... See more

A new position in David Poppe’s Giverny Capital - Medpace Holdings, providing clinical trial tests for small biotech companies. The founder owns 17%, stock at 25x PE.
$MEDP
The link to the full Q3 letter in reply. https://t.co/5ktdHceiDS

Wonder what that secretive longevity company funded w/ $3B from @JeffBezos and @yurimilner has been working on?
SCOOP: @altos_labs latest public program is an oligonucleotide inhibiting the retrotransposon LINE-1 to treat progeria. https://t.co/ynsQL2sT8X