Sublime

This voyage is my own attempt, as a biochemist, to find the inner meaning of the Krebs cycle: why it is still spinning at the very heart of life and death today.

oxygen levels are low, one prong consumes NADH (shown here as 2H) while the other generates it. Together, they maintain a poise between the donors and acceptors of 2H, while allowing a little ATP synthesis on the side.

In the 1930s, Max Kleiber, a Swiss agricultural biologist, observed that, across mammal species, from shrews to elephants, the energy required to maintain basic metabolic function is closely correlated with an organism’s body size.

we cannot assume that everything interesting is at the same scale as ourselves.