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Today, we report Germinal, a method for efficient de novo antibody design, with @santimillef and @SynBioGaoLab.
Germinal achieves success rates of 4-22% across diverse epitopes.
We make the work fully open, without doing lame things like posting a preprint without methods. 🧵... See more
Longevity is now for embryos.
Nucleus Embryo is the first-ever genetic optimization software that helps parents give their children the best possible start in life — long before they’re even born.
Longevity was never just about health. It’s about thriving.
That’s... See more
Kian Sadeghix.com
The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science.
Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving 4–22% success rates with efficient experimental validation.
I’m sharing the following details that may be useful to you:
(1) Plasmid Full Name:
pTRE3GBi_EF1A_Tet3G_IRES_Puro-VHH hFBXW11-mCherry
or pTRE-BI-hGRAD
> Bacterial Resistance: Ampicillin.
> Addgene Link: https://www.addgene.org/207837/
(2) Reference Paper:
https://rupress.org/jcb/article/223/2/e202304030/276463/hGRAD-A-
... See moreKimera Chems
kimerachems.co
Daily dose of #Diatype (unreleased) 💉🦠💫
instagram.comRetatrutide - Research Dosing
researchdosing.com