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why don’t we have more medicines?
inventing medicines has grown less efficient, limited by our knowledge of biological targets
for the 1st time, AI & genomics have the potential to make this knowledge abundant – one of the largest potential impacts of the intelligence age.

Excellent blog post by @jacobkimmel on why pharma progress has slowed down over the last many decades, and why some people are optimistic about a big speedup over the next few years.
Eroom's Law (coined by @jackscn) says that the number of drugs per billion dollars decline two-fold every nine years.
___LIN... See more


Okay Grok: build a startup that can run 500 complex health tests from a single drop of blood. Make no mistakes. And no fraud. https://t.co/ybqeIGTs21
Trends – Artificial Intelligence (AI) – May 2025 – BOND
The document analyzes rapid growth and transformative trends in artificial intelligence, highlighting unprecedented user adoption, technological advances, global competition, enterprise AI integration, and associated benefits and risks shaping the future.
bondcap.com
Nice article (h/t @KRHornberger ) explaining why current AI approach is unlikely to help drug discovery, and particularly $rxrx because they are looking at the least impactful stage; generating hits. https://t.co/HKiP6SbdiP... See more
10 bio companies on the edge of legality and ethics:
- Alcor - freezes people after death (running since 1974; >200 people frozen)
- Viagen - clones animals like cats, dogs, and horses for private owners
- Nectome - brain preservation co aiming at long-term memory preservation (Sam Altman on waitlist)___LI... See more
Dr. Shelbyx.comLet me tell you a story. It'll end up at the current tech-bio and protein design scene.
But the story starts about 25 years earlier.
Did you know that, commercially, the human genome project precipitated the end and not the start of a genomics boom? 1/
Rohit Singhx.com