Sublime
An inspiration engine for ideas
Anyone else tracking the non antibody/small molecule space in public markets? Like we've seen with the microbiome space, we'll see the tail or head winds in related modalities for years to come! 🧬
Especially interested in macrocycles with @Merck, BMS, @Cothera, Bicycle, Revolution Medicines, Chugai all in clinic. ___LI... See more
Neil Parikh
@njp
Sotiris Kaniras
@castashuman
Nikolas Steiner
@nemo
Bob's Med Chem Fact of the Day:
Shionogi's new SARS-CoV-2 3CL protease inhibitor is a great example of how obtaining ADME info on screening hits can be helpful.
They took a hit with modest potency (8 uM triazine!) but promising PK profile, and quickly obtained a candidate. https://t.co/YhyQ3Q5xcC
Are Blockchains Decentralized? Unintended Centralities in Distributed Ledgers
The report investigates the true decentralization of blockchains, highlighting various forms of centralization, vulnerabilities in consensus protocols, and the implications for security and immutability in networks like Bitcoin and Ethereum.
blog.trailofbits.comThe Non-Niche
@nonniche
Nico Sakaki
@nicosakaki
artist trying to make art. writer trying to write. human trying to human. occasionally succeeding at all three
Daniel Kazandjian
@dkazand