Sublime

If the nerve cell membrane is too rigid, receptor availability is impaired and can result in dysfunctional signaling, thus influencing our moods, behaviors, and memories.

One of them was an enzyme, appropriately anointed Dicer,

Walter Bradford Cannon, the legendary Harvard physiologist who first coined the term “fight or flight,” and popularized the term with his book The Wisdom of the Body. 1

Remarkably, about half of all useful antibiotics target bacterial ribosomes.

houses the catalytic center, which is responsible for stitching together amino acids, one after another, to produce the chain of amino acids that we call a protein.

Scientists discovered that DNA is able to exert control only because enzymes, like most proteins, live fast and die young. Most degrade after a few hours or days.52 So it’s the highly choreographed sequence in which genes call for (or don’t call for) the production of new enzymes that controls most of the action within a cell. It is the changes in

This means keeping watch for the earliest signs of trouble. In my patients, I monitor several biomarkers related to metabolism, keeping a watchful eye for things like elevated uric acid, elevated homocysteine, chronic inflammation, and even mildly elevated ALT liver enzymes. Lipoproteins, which we will discuss in detail in the next chapter, are