Sublime

kinases† that activate protein p53, which is sought after because it curbs the growth of cancers.

This voyage is my own attempt, as a biochemist, to find the inner meaning of the Krebs cycle: why it is still spinning at the very heart of life and death today.

Remarkably, about half of all useful antibiotics target bacterial ribosomes.

Already a physician, Bradner went back for further study in chemistry with the goal of developing targeted drugs that can disable cancer cells’ growth at the molecular level. From the beginning,

U6 enters the scene tightly entwined with U4, and together they find their place on the intron. But then U2 butts in, stealing away U6, and U4 exits the stage in a huff. Now U6 and U2, with some help from U5, are free to produce the chemistry needed to complete the splicing reaction. Together they act as a ribozyme, catalyzing the mRNA splicing pro

a German physicist named Fritz-Albert Popp had stumbled upon the fact that all living things, from the most basic of single-celled plants to the most sophisticated of organisms like human beings, emitted a constant tiny current of photons—tiny particles of light.15