Sublime

All forms of refined, processed carbohydrates:

The First Principle The only proven strategy for slowing aging and prolonging lifespan is moderate calorie restriction in the environment of micronutrient excellence. The Second Principle A diet has to be hormonally favorable to enable maximal lifespan. The Third Principle Optimal exposure to all macronutrients and micronutrients humans require is

Scientists have concluded that its byproduct, AMP, triggers mitochondrial growth.

The reason rapamycin has so many diverse applications is thanks to a property that Sehgal had observed, but never explored, which is that it tends to slow down the process of cellular growth and division.

More mitochondria, means more oxygen—a big win for endurance athletes! Research is still in the early days—all the studies being done in mice, not humans—but this could be the next wave of supplements.

The best way to clean up and rejuvenate old mitochondria is to eat a whole foods low-starch-and-sugar, good-fat, microbiome-supporting, polyphenol-rich diet, practice intermittent fasting or caloric restriction, and incorporate hormesis (good stress) routines like cold plunges or showers, aerobic exercise, strength training, and a few key supplemen