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The Fabric of Reality: The Science of Parallel Universes--and Its Implications
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The Beginning of Infinity
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we cannot assume that everything interesting is at the same scale as ourselves.
John Brockman ⢠This Will Make You Smarter: 150 New Scientific Concepts to Improve Your Thinking (Edge Question Series)

For highly adapted replicators (which are the only ones worth calling replicators) we need consider only fairly small variations, because under most large variations they would no longer be replicators.