sari

Santos, dark-haired and so striking-looking one website referred to him as “the brains (and beauty)” behind the operation, was the CEO. Nathan, who had a shaved head, sometimes with a beard, was the chairman. They started the company with $400.

I’ve seen a lot of new patient communities pop-up recently. I think it’s the combination of communities being the hot topic in VC land, the idea that communities provide some sort of defensibility for a product, and the fact that everyone is online now and exploring new parts of the internet.

As CEO, I have the most context of anyone at the company, so all uncertainty is fully contextualized for me. An associate-level team member may have 10% of the context I do. Even if you communicate diligently and transparently, variables like fundraising climates, board member dynamics, program prioritization, how decisions are made, personal prefe... See more

The most important decisions in your life may be whether to marry, who to marry, and whether to have kids. But none of those topics are taught in school. They’re hardly even discussed. How could they be? They aren’t problems you can distill down to an equation, or even a broad principle.

While a tad oversimplified, Charlie Munger’s famous one-liner is sort of like the Occam’s Razor of human behavior – especially at scale. People are generally far more driven by self-interest than by any other factor.

The criticism of blockchain that has most effectively stuck, understandably, has been its ecological cost. The facts are, truly, atrocious. By one estimate, the creation of one basic NFT involves as much energy as driving a car 1,000 kilometers.