nico λ

Addiction is in all of us. This argument has come to matter a great deal to me. The reason I care about it is that when I truly felt this notion in my bones, reading accounts of addiction and recovery from across history, it was profoundly reassuring and comforting. As I write at more length in the book, I developed a sense of fellowship with all... See more

Also, psychedelics have a fundamental discordance with allopathic research which can never be overcome. The placebo problem is unsolvable. And these medicines are customarily adjacent to non-directive therapy, and ongoing integration. We'll never be able to quantify those things in a trial format the same we we can for a blood pressure pill.... See more

Studies have shown promise in treating Alzheimer’s and Parkinson’s with GLP-1 drugs, perhaps by regulating insulin levels and reducing inflammation, and the drugs may yet prove useful in treating many other conditions made worse by chronic inflammation. Some studies have found large decreases in the risk of depression and anxiety; others found... See more

The search for root causes often means a life event that has triggered the mental disorder. When I hear people talk about root causes, it usually means they are not happy with a biological explanation and want something more psychological, more meaningful, more profound.

In clinical practice, this is tricky though - we can rarely, if ever, put our... See more

Many of us yearn for a way to be fully online without all of the mindlessness, passivity and addiction that often entraps us. Some of us oscillate between fully online and fully offline in a sort of mad dance to establish what feels right. Others have lost hope that it’s possible to engage in a way that feels true and alive, and have resigned to... See more

But I think perhaps the main element in Musk’s radicalization is simply the feedback loop of the internet - Musk has millions of fan-boys cheering on his every lurch to the right, every tweet about immigration or Anthony Fauci or the ‘woke mind virus’. He’s a transhumanist enslaved by his own machine, a wizard deceived by the demon algorithm which... See more