nico λ

More and more, I think my issues with conventional productivity advice – indeed, with the very notion of productivity – boil down to this: Spending your days trying to get through a list of things you feel you have to do is a fundamentally joyless and soul-destroying way to live; and most productivity problems, like distraction or procrastination... See more

This designation is based on the direction the compound rotates polarized light that's shined upon it. If it rotates the light clockwise, it's dextrorotatory, and it's referred to as right-handed. Counterclockwise = levorotatory = left handed. It's important in biochem, not only because biological systems tend to differentiate between the two, but... See more

And speaking of things that work even more less good, the technology... sucks? It fundamentally doesn’t do the thing that its investors and diehard fans say it does. It just strings together text that is statistically plausible. And every new alleged advancement comes with some invested airhead billionaire boasting about how the computer is as... See more

ours is an era of decline that has turned from the outward to the inward obsession with identity and “authenticity,” both personal and tribal, fueled by digital connectivity. Paradoxically, social media in this sense is anti-social, leading to the disintegration of community through a kind of connected isolation.

i really hate that computing and STEM have this mystique in our society. to the extent that engineering demonstrates intelligence, it's by repeatedly forcing you to confront the results of your own mistakes , in such a way that errors can't be ignored. there are lots of ways to do that which don't involve programming or college-level math!... See more

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This probability of obtaining another data set as extreme as the one collected is known as the P value. The P value is often criticized for being misunderstood and misused in the field of medicine.2,3 For example, in contrast to popular belief, the P value is not a measure of how correct a hypothesis is, nor is it a measure of the size or... See more

In this respect, Bayesian inference is more intuitive at its core and in closer alignment with our natural mode of probabilistic reasoning than frequentist inference. For example, we are more interested in the probability that 1 treatment is superior to another (Bayesian probability) than in the probability of obtaining certain data assuming the... See more

## In Conclusion

1. CLAUDE.md is for onboarding Claude into your codebase. It should define your project's WHY , WHAT , and HOW .


2. Less (instructions) is more . While you shouldn't omit necessary instructions, you should include as few instructions as reasonably possible in the file.


3. Keep the contents of your CLAUDE.md concise and universally

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