Matej Šarlija

"Pathologists are now tasked with specifically identifying the intricate subtleties of HER2 expression dynamics across a wider continuum, an aspect that was previously deemed clinically irrelevant."

Archiving both glass slides and WSIs in routine practice is not cost effective and will require extra resources, however, it is unlikely that pathology laboratories will abandon storing glass slides and rely on the archived the digitized WSI unless there is evidence-based reassurance that WSI is fully representative of the corresponding glass... See more

At the same time, he boasts that about 70 percent of the data in electronic health records comes from pathology departments.

Instead of any reductions, digital pathology will require additional workflows, personnel, equipment and, most importantly, storage of data.”

Whereas Radiology is a specialty that typically renders impressions, Pathology typically offers the definitive discriminant power of a true diagnosis, along with any associated prognostic / theranostic value-added data. Although a radiologist is asked to render impressions on received images alone, a pathologist is tasked with the generation of... See more

Clinical pathology has always gone beyond the interpretation of a single WSI.

While Z-stacking enhances the AI algorithm's inferred quantity and coverage rates of atypical cells, it simultaneously results in longer scanning times and larger image file sizes.

The main benefits are a more convenient case organization and distribution of work,16, 17, 18 allowing remote consultation19,20 and the possibility to work from home.19,21, 22, 23, 24, 25, 26, 27, 28 Moreover, cases at multidisciplinary meetings (tumor boards) can be presented more efficiently in digital form,15,29,30 and teaching/training27,31,32... See more

We next sought to understand the drivers and barriers to the adoption of AI-guided image analysis (also referred to as computational pathology or CP). The top value proposition for AI-guided analysis is to enable biomarker detection that is difficult or impossible to score manually, such as PD-L1 (Figure 3).