Juan Orbea

But the outlook of these young people can't be explained by economics and global events alone. It must also have something to do with the way they were raised. As the University of Michigan time-analysis data show, this is a group whose members have spent the bulk of their lives in structured, adult-organized activities. They are the most honed and... See more

A classic problem in computer science is hill climbing. Imagine you are dropped at a random spot on a hilly terrain, where you can only see a few feet in each direction (assume it’s foggy or something). The goal is to get to the highest hill.

Nodes, which in this case are people, exchange a host of things. Sometimes consciously if I pay you from my bank account, sometimes unconsciously like when you overhear me at dinner telling someone about how I coach founders during walks and you decide to try it with your employees. The nodes exchange more of these things when the friction is low... See more

Listen to Henry tell his story from learning about effective altruism to making the decision to giving away 50% of his income - he also shares a fascinating story about getting infected with malaria for medical research.

You might agree that future people matter in the abstract. But it’s this point — that our actions today could meaningfully impact their lives — that might compel you to believe that positively influencing the long-term future should be a key moral priority of a time. This is the idea encapsulated by longtermism.

It takes 1.3 billion dollars to get though the FDA process.

Of these companies that become well financed we only need 15–25% of those to pan out to return 2–3x the fund. But this is all driven on the assumption that we didn’t write a $20 million check out of the gate, that we didn’t pay a $100 million pre-money valuation and that we took a meaningful ownership stake by making a very early bet on founders... See more