Juan Orbea

Thiel argues that innovation has stagnated in the last half a century, citing examples of how industries like energy, aerospace, automotive or biotech haven't had any major breakthroughs during this period.

At some point in the 90s Coca Cola was 40% of BH’s portfolio, and they made a 13x on the investment during the next decade

Is there really a straight line between you and the things you want in life? Entrepreneur and educator Luke Burgis goes deep on how understanding mimetic desire can help you better connect the dots between where you are now, and where you want to go. 

In short, VCs in these frontier domains essentially need multiple miracles for these companies to succeed. Compare those scale up challenges to traditional biotech and pharma, where the entire industry has designed systems and processes to prove safety and efficacy and grow production. There’s still serious technical risk, but it’s knowable technic... See more

Is the human brain different from a computer?The answer depends on what we mean by the word “computer.” Certainly the brain uses very different methods from conventional contemporary computers. Most computers today are all digital and perform one (or perhaps a few) computations at a time at extremely high speed. With regard to digital versus analog... See more

So Chris tried his hand at chipping away at this problem — but concluded the nature of the problem wasn’t quite what he originally thought. In this conversation we talk about that, as well as:

Canva's target market has always been the long-tail of less sophisticated creatives, often people without technical skills or advanced software. For that long-tail, the focus is on creating high quality designs with as little friction as possible. By bringing all of this creative surface area into the same platform they enable long-tail creators to... See more

Balaji outlines a few ideas for network states, which I will condense into two key directions: lifestyle immersion and pro-tech regulatory innovation.