Collections

Startups173
Alex Wittenberg

When startups start taking off, the founders usually can't tell what's changed. It's some combination of all the random things they did to make it ta

Enzyme Biomodeling1
Juan Orbea
Artificial Intelligence243
sari

Most AI backlash is economic anxiety coated in a veneer of social justice. Alfalfa farming consumes 19 times the water that data centers do; there’s n

“Diffusion lag” reflects a lack of product-market fit. Even AI optimists are still hitting practical roadblocks. That’s why detailed case studies are

Here are some things I’ve asked chatgpt recently: “why is Toblerone so popular at airport duty-free stores?” “give me a recipe for a chickpea tagine

synthetic biology 7
Juan Orbea

Dallas-based Colossal Biosciences, the self-described de-extinction company behind the woolly mammoth and thylacine, today announced that it is spinni

computational biology2
Juan Orbea
Complex Systems42
Jason Badeaux

“leverage points.” These are places within a complex system (a corporation, an economy, a living body, a city, an ecosystem) where a small shift in on

Leverage Points: Places to Intervene in a System

Future of Wealth Management and Investing23
Timothy Shih
investing wisdom58
Daniel Bakalarz
pdf
Investment thesis17
Darren LI

Instead, Professor Kahneman favored an alternative that he termed “adversarial collaboration.” When people who disagree work together to test a hypoth

Julian Shapiro1
Juan Orbea
Koko Xu1
Juan Orbea
deep-tech33
Juan Orbea
Early Career Advice58
Kassen Qian

Advice I would give to a college freshman: These next four years, one of your main goals should be to figure out how not to have the rest of your lif

Life243
Prashanth Narayan

The hyperreal doesn’t mimic or imitate reality. It replaces reality altogether, making it nearly impossible for us to determine what is real, what isn

I say please and thank you, not because I believe it matters to him, but because it matters to me. If I am going to use natural English to communicate

Every phase of life can be shopped for at Costco. Where else can you purchase a wedding ring, a baby carrier, and a casket? It follows your own life s

when i'm tied up in consumption, creation is lost to me; i am no longer the writer, the creative, the poet, the artist, but the eater, the viewer, the

Life Advice82
unoptimal

Novelist Charles Kingsley on happiness: “We act as though comfort and luxury were the chief requirements of life, when all that we need to make us hap

And I came to believe that heroism is neither being perfect, nor doing something spectacular. In fact, it’s just the opposite: it’s regular, flawed hu

neurotech11
Juan Orbea
Real Learning1
Juan Orbea
Future of Education and Learning324
sari

In large part this is because education, like most social systems, is slow to adapt, iterate, and evolve to be relevant for changing times. The glacia

generative AI is but the latest in a line of innovations that draws attention to the flaws of the modern education system, leaving us to question how

The humanities, rightly understood, are the things that technology cannot take away or substitute for. Of course, I don’t mean ‘humanities’ in the way

Learning Science3
Bhaumik Patel
Investment memo19
Darren LI
Alternative Asset Investing68
sari
Value Investing11
Daniel Bakalarz

If alpha is the ability to earn return without taking fully commensurate risk, investors possessing it can do so by either reducing risk while giving

Dreams1
Juan Orbea
Neuroscience95
Abie Cohen

“Worry can become like a bad habit of the mind. The rule of neuroplasticity—that our brain keeps changing based on our repeated activity—says that wha

many of the quant-ities related to suffering are based on perceptions and similar uncertain infer-ences. The uncertainty will necessarily increase fru

Scientists have demonstrated that, as the years go by, much of what we think we remember is false. It seems our brains can't store every detail we exp

Psychology134
sari

The Science Finally Catches Up: New Research Confirms ADHD as an Evolutionary Advantage, Not a Disease

a career you love105
sari

When pursuing a 1-of-1 vision, you aren’t going to be the most popular or celebrated person. You’re going to be an oddity that the most in-the-know pe

It’s possible for other projects to be sexier, more lucrative, and more attention getting, however their purposes are less unique than yours.

I appreciated Nvidia’s founder talking the other week about what it means to work in a zero billion dollar industry. It means really believing in some

Personal Development299
sari

That is, be systematically ascetic or heroic in little unnecessary points, do every day or two something for no other reason than that you would rathe

Traumatisation is most usually presented as anunassailable, concrete fact, and this is where I need to be respectful. If someone brings a firmconvicti

when the trauma label has been appliedby outside mores – when an event like an explosion, an assault or a sexual event has taken place andour culture

personality13
Juan Orbea

Always stick to what makes you weird, odd, strange, different. That’s your source of power.

Introduction Document 1 Version 1 #MundiaModiaDrafts I welcome feedback, both on the ideas, and on the presentation of the ideas. Mundia & Modia: T

Competition3
Juan Orbea

Brian at Reforge says: One of my strong beliefs is that startups should rarely think about competitors and most should think about alternatives. Alter

“This is something I was thinking about when I was interviewing Patrick. In some sense, when he started Stripe, payments was a super crowded industry.

Creativity299
sari

www.simonstalenhag.se

The text actually moves back and forth between all of these. Few novels pay less attention to the rules of fiction than Zen and the Art of Motorcycle

surprise may be a better proxy for creativity than quality. A polished output is not necessarily creative, but a surprising one might be. Yet even sur

curiosity74
Prashanth Narayan

No one talks about the way in which the world, in all of its bewildering capability, is, at every second, offering some detail that might lead to a ne

“to hone sensory receptivity to the marvelous specificity of things.” I would argue that this is another way of talking about learning to pay a certai

hello, i'm v good at asking questions. it's one of the things i get most complimented on i think what i do is simple & easy for anyone to do: 1.

Intelligence is a form of friendship with the world. It can’t be cultivated out of fear of it.

Deep-tech VC funds15
Juan Orbea
Quantum hardware1
Juan Orbea
Quantum Computing1
Juan Orbea
Renewable Energy21
Johanna
Energy21
Johanna

Stephen Malina

Sustainability & Climate Change217
sari

The destiny of our species is shaped by the imperatives of survival on six distinct time scales. To survive means to compete successfully on all six

We need the right kind of climate optimism

We Need the Right Kind of Climate Optimism

hedge funds5
Juan Orbea

Letter to a Friend Who May Start a New Investment Platform

Luxury Economy & New Luxury53
sari

Host: And of course, the luxury sector spans over so many different products. But what do you think the definition of luxury is?Bernard Arnault: First

to be successful, you have to have the combination between modernity and timelessness.

How Hermès Sells "Time"

Electric Boats1
Juan Orbea

Twin Vee & Forza X1 analysis - $VEEE $FRZA - MORAM Capital

Electric Vehicles10
Jason Badeaux

Twin Vee & Forza X1 analysis - $VEEE $FRZA - MORAM Capital

Boats1
Juan Orbea

Twin Vee & Forza X1 analysis - $VEEE $FRZA - MORAM Capital

Small caps1
Juan Orbea

Twin Vee & Forza X1 analysis - $VEEE $FRZA - MORAM Capital

Microcaps1
Juan Orbea

Twin Vee & Forza X1 analysis - $VEEE $FRZA - MORAM Capital

Portfolio construction1
Juan Orbea
Poker0
Juan Orbea
Crypto251
sari

By yielding a generational wealth creation opportunity that was a strange hybrid of a lottery jackpot and self-made fortune, crypto created an ideolog

For example, it was 30 years after the invention of film that someone first tried telling stories with it — before that, film was mainly used as a dem

Just a moment...

How do you explain the web to people who have never used it? You make it as simple and as accessible as possible.

music172
Yufa

Hellman & Friedman's majority stake in Global Music Rights marks a watershed moment — private equity firms now control three major PROs (alo

Gen AI  for music has captured ~$300M in funding so far this year across several high-profile deals, the majority of which either focus on  rights man

mac.are.na

satire1
Juan Orbea
Bits and Atoms13
sari

on digital vs physical interactions: Life is a conversation and you need places to have it. The virtual provides us with more spaces for these convers

Entrepreneurship64
Mark Fishman

It’s about the same trap in professional life: doing the thing for years, getting more experienced, and staying stuck at the same level. You can work

I don't know if I'm ever going to get rich doing this but I am going to keep making things that I want to exist, in a way that seems fun and to a leve

What we see as an agency in our work with creatorsWe work with a lot of creators around the world for different brands, markets and niches and the one

So who survives?First, creators who publish citable work. Newsletter writers who go deep on one thing. Analysts who publish original data. Technical w

venture capital terminology1
Juan Orbea
venture capital55
Juan Orbea
Term Sheet1
Juan Orbea
Natural Language Processing (NLP)16
sari

People need to be more thoughtful building products on top of LLMs. The fact that they generate text is not the point.

niche markets2
Stuart Evans
Startup Growth104
sari

Aggressive growth projects often lead to UX cruft, slowly degrading long-term user engagement and retention. Yes, you can move short-term metrics by t

Founder Mode

Philanthropy6
sari

Spirits and Logistics: How Grantmakers, Universities, and Arts Institutions Start Working with the BIPOC-Led Cooperative Movement to Build the Future

Biography5
Jay Matthews

The Reluctant Prophet of Effective Altruism

Philosophy118
Brian Sholis

The man we call an adventurer...is one who remains indifferent to the content, that is, to the human meaning of his action, who thinks he can assert h

Business Models60
sari

I came of age in the Napster days, when only fools spent money on anything digital. Early on, we decided that we’d rather pay for the internet with at

One mistake I often used to make at Justin.tv was offering a potpourri of business models (virtual goods, product placement, chat ads, contests, etc..

The problem in media isn’t the business model. The problem is that most of the content sucks.

Creator Collaboration42
sari

If we give them the room to breathe, creative works can live multiple lives. The works will stay online for years, decades even. It will make someone

What they don’t see, and what we continue to experience, is that while collaborating can be hard, it’s also a more rewarding, fruitful, and uplifting

I’ve been thinking about the enduring, perhaps increasing currency of personal recommendations (practically artisanal craft now if you think about it!

Knowing where to go and what to do is the currency that, in the modern aspiration economy, makes curators more important than influencers. They guide

influencer culture143
sari
how can creators monetize?199
sari
The Creator Economy524
sari

Similarly, I wonder whether the creator economy, as it matures, will resemble less of its original promise (a way for people to do the things they lov

Generative AI133
sari

编程这项工作非常适合 AI 增强或替代,原因如下:1/ 编码本质上要求工程师将问题分解成更小、更易管理的任务;2/ 有大量现有的训练数据;3/ 任务需要判断力和基于规则的工作相结合;4/ 解决方案利用可组合的模块(比如开源软件库等);5/ 在某些情况下,工作成果可以通过经验测试其正确性。这意味着可靠

AI is aggregated human intelligence. So it’s better to call it collective intelligence than artificial intelligence. Emphasizing the collectivity (som

AI Art29
Jenny Nicholson

anxiety surrounding AI art is less about computers becoming humans and more about humans becoming more robotic. social media is robotic, formulaic. ev

As Kevin Abosch, the Irish conceptual artist and pioneer of blockchain art, aptly put it: “The wise artist doesn’t fear emergent technology, but rathe

Brain computer interface6
Yash Mimani aka ahafisher
Synthetic Media68
sari

Razorfish Study Finds 52% of Gen Z Gamers Feel More Like Themselves in the Metaverse than in Real Life

Digital Identity52
Jilber Najem

We can always opt out of this arrangement, of course, and live happily in meatspace, but that is precisely the point: Offline we exist by default; onl

We are currently living in a time when the lines between fantasy and reality are blurring and virtual worlds are creating room for new rules of self-e

Algorithmic Surveillance4
Keely Adler

The vast interconnection enabled by digital platforms has ended up creating more of a sense of sameness than diversity. Users are subtly guided toward

cybercrime1
Juan Orbea
IT Compliance & Cybersecurity6
Austin Castellaw

Here are 12 great threads about crypto that will help you become a better investor: /THREAD

market sizing1
Juan Orbea
Market Research8
sari
semiconductors3
Jilber Najem

The Changing Face of Compute

fiber optics1
Juan Orbea
founder's mentality262
sari

Don’t shrink the vision to fit the doubt

Govtech12
sari

Du Pont Bomb memo

3D Printing2
Juan Orbea

Troodon 2.0 Pre-assembled Fully-enclosed CoreXY 3D Printer

Future of Housing10
Mo Shafieeha
social systems32
Juan Orbea

Environments are emotionally contagious, and if the environment you spend a lot of time in is hyper-competitive and performative, you’re going to feel

Capitalism40
Prashanth Narayan

“It’s easier to imagine the end of the world than the end of capitalism,” wrote the literary critic Fredric Jameson. One of the hardest elements to im

While serving a life sentence in jail, Kaczynski wrote a little-known sequel to his manifesto, entitled “Anti-Tech Revolution: Why and How”. In it he

As a society, we are so fully invested in capitalism, competition and algorithms that it’s almost impossible to pull ourselves out of the cycle to see

economic growth54
Johanna
pdf

Longtermtrends - Quarterly Chart Brief - October 2024 | https://eocampaign1.com/web-version?p=bb6d40de-a003-11ef-99eb-311c7e9fb2a9&pt=campaign&t=1731

information theory2
Juan Orbea

The Zapatistas and the Electronic Fabric of Struggle*

democratization of artificial intelligence4
Juan Orbea
russia1
Juan Orbea
emerging markets1
Juan Orbea
Hiring Advice93
sari

People who don’t take themselves too seriously. They have to be able to laugh at themselves to succeed. What to look for: This is usually very easy to

The #1 thing I look for when hiring people is FIO. "Figure It Out" You can get pretty damn far just by being: - Resourceful - Reliable - Results or

@mckaywrigley I have a bunch of questions I ask. What would you build for yourself? What did previous companies you've worked for need? What are you a

Non-Fungible Tokens (NFTs)300
sari

Digital Object ApplicationsFor the first time in human history, blockchains empower any digital object to enjoy the properties of verifiable scarcity,

Web 3.0524
sari
Metaverse185
sari

1/ The good news: the METAVERSE is exciting but NOT for the reasons most people are talking about. The bad news: odds are the 'Metaverse' will be us

Whether it is through a VR headset, the manipulation of projectors, or clever set design, immersion fulfills our desire for escapism, instantly transp

AR/VR 37
Sam Blumenthal

ARKit persists anchors and mapping data based on your location. Practically speaking, this means that if you use an app to anchor some paintings to yo

Science45
Yufa

If you have a theory that’s been working pretty well for a while — it made good predictions, it solved real problems, it explained a lot of mysteries

Real explanations will sometimes sound weird, crazy, or too complicated because reality itself is often weird, crazy, or too complicated. It’s unfortu

Things change as contradictory evidence piles up, but even then, it doesn’t mean you should scrap the theory you started out with. Everyone back in th

what is Social Media doing to us?239
Jerod Morris

We all know we’re overstimulated and want to stop, but we can’t. We use app blockers, throw our phones away, and build rigid routines. But none of it

humans don’t have fixed identities. we’re constantly testing. trying different versions of ourselves. seeing what gets rewarded. adjusting based on fe

I feel like there’s something so soulless about our culture—something deeply, deeply missing in people’s experience of life, a kind of superficiality.

Governance90
sari
Network states3
Juan Orbea

What do I think about network states?

AIGC (Artificial Intelligence generated contents)4
Darren LI

LibLibAI - AI-Powered EPUB Library and Ebook Reader

AI alignment10
Juan Orbea

Whether or not we come to understand “intelligence” any time soon, we do have a major challenge on our hands in bringing together computers and humans

existential risk3
Juan Orbea