Johanna

First off, goals have an endpoint. This is why many people revert to their previous state after achieving a certain goal. People run marathons, then stop exercising altogether.(...) Second, goals rely on factors that we do not always have control over. It’s an unavoidable fact that reaching a goal is not always possible, regardless of effort.(...)... See more

Pretty soon, it becomes surprisingly easy to fill a full work day simply responding to whatever pops up instead of intentionally working on the highest priority things. We can easily fall into the trap that I described in the intro where we outsource our prioritization with whatever comes up.Without a trusted way of saying to ourselves and our... See more

The picture this survey paints is bleak: Over the past century, we’ve vastly increased the time and money invested in science, but in scientists’ own judgement, we’re producing the most important breakthroughs at a near-constant rate. On a per-dollar or per-person basis, this suggests that science is becoming far less efficient.

The worthwhile problems are the ones you can really solve or help solve, the ones you can really contribute something to. A problem is grand in science if it lies before us unsolved and we see some way for us to make some headway into it. I would advise you to take even simpler, or as you say, humbler, problems until you find some you can really... See more

No blinding. Experiments must have a test and a control arm. “Blinding” is when the researcher doesn’t know whether the subject they are analyzing (be it proteins, cells, mice, or human subjects) is the test or the control. Results are more reliable if the researcher is blinded, and this is standard part of clinical trials, but is often not... See more