A child who has watched a parent solve a problem gains enormous strength from that.

Eventually, you are simply absent from yourself.

activated depression

A terrible imminence overtakes entirely the present moment.

“Families must guard themselves,” Kay Jamison once said to me, “against the contagion of hopelessness.”

druthers,

the field of depression, psychological stress transduces to biological change, and vice versa.

It is clear that stress drives up rates of depression. The biggest stress is humiliation; the second is loss.

“Our view is that most depression is antisocial in origin; there is a disease entity as well, but most people are able to produce major depression given a particular set of circumstances. Level of vulnerability varies, of course, but I think at least two-thirds of the population has a sufficient level of vulnerability.”