Sickle cell disease, sleep disorders and lung cancer: these are just a few of the medical issues that were under investigation in at least 383 clinical trials that have had research grants terminated by the National Institutes of Health since February.

That’s about 1 in 30 of all the clinical trials—tests of medical interventions in human volunteers—funded by the federal agency, which has a $48-billionresearch budget, according to a JAMA Internal Medicine study published Monday.