Fentanilo - Wikipedia, la enciclopedia libre

This phenomenon, widely observed and verified by animal studies, has come to be called opioid-induced hyperalgesia. Algesia, from the Greek word algesis, means sensitivity to pain. What’s more, when these patients tapered off opioids, many of them experienced improvements in pain.

“As nitrous oxide... appears capable of destroying physical pain,” Davy wrote, “it may be probably used with advantage during surgical operations...”

Endorphins and anandamide, our final two pleasure chemicals, are pain-killing bliss producers. They’re both heavy-duty stress relievers, replacing the weight of the everyday with a euphoric sense of relaxed happiness.

A 2016 report from the Surgeon General highlights the pain that people are experiencing. Among the findings: “More people use prescription opioids than use tobacco.