Endometriosis remains one of the most poorly understood conditions due to its molecular, hormonal, cellular, and heterogeneric complexity, and an overall lack of funding for research into female-only diseases (Smith, 2023; Zondervan et al. , 2023).

Endometriosis affects an estimated 190 million women (and those assigned female at birth) worldwide, with a significant personal and societal burden due to its painful and fertility-related symptoms (Nnoaham et al. , 2011; Zondervan et al. , 2020)

The overwhelming prevalence of endometriosis and the unknown aeteology highlight the need for a better understanding of the basic biology of endometriosis formation and persistence to enable subsequent identification of targets for effective therapies for endometriosis.