A Guide to DeSci, the Latest Web3 Movement - a16z crypto

Still in its infancy, DeSci lies at the intersection of two broader trends: 1) efforts within the scientific community to change how research is funded and knowledge is shared, and 2) efforts within the crypto-focused movement to shift ownership and value away from industry intermediaries.

What primarily differentiates DeSci from other efforts to rethink our research system is its use of blockchain tools. This is similar to how blockchain is disrupting other industries, where web2 models of centralized ownership are being challenged by web3 models of decentralized, shared ownership.

Funding is an especially acute pain point for scientists, who spend up to half their time writing grant proposals. Success in getting funding is heavily tied to metrics such as the h-index, which quantifies the impact of a scientist’s published work. The resulting pressure to “publish or perish” incentivizes the pursuit of novel research over work ... See more